Tecan IBL International offers a comprehensive range of ELISAs, antibodies, immunoassays and recombinant proteins for research use only.
Leucine-Rich Alpha-2-Glycoprotein (LRG) ELISA Kit
Purpose: The Leucine-Rich Alpha-2-Glycoprotein (LRG) ELISA Kit is specifically designed to measure LRG levels in rat samples. This assay facilitates the study of LRG's role in various conditions, including rheumatoid arthritis (RA) and idiopathic normal pressure hydrocephalus (iNPH).
Background: Leucine-rich alpha-2-glycoprotein (LRG) is a member of the leucine-rich repeat protein family. It is involved in various biological processes, including protein-protein interactions, signal transduction, cell adhesion, and development. Recent research has highlighted the following key roles and associations of LRG:
- Rheumatoid Arthritis (RA): Elevated serum levels of LRG have been observed in RA patients compared to healthy controls. LRG levels tend to decrease following effective anti-TNF therapy, making it a useful biomarker for monitoring disease activity and treatment response in RA.
- Idiopathic Normal Pressure Hydrocephalus (iNPH): Increased LRG levels in cerebrospinal fluid (CSF) have been associated with iNPH. Measuring LRG levels can aid in distinguishing iNPH from other neurodegenerative conditions with similar symptoms, such as Alzheimer’s disease. Additionally, LRG levels can be used to assess the effectiveness of shunt therapy in iNPH patients.
Significance: Accurate measurement of LRG is valuable for understanding its role in various pathological conditions. This ELISA kit enables researchers and clinicians to monitor LRG levels, which can provide insights into disease mechanisms, treatment efficacy, and differential diagnosis.
Assay Details:
- Detection Method: Enzyme-Linked Immunosorbent Assay (ELISA)
- Target: Leucine-Rich Alpha-2-Glycoprotein (LRG)
- Specificity: Designed for precise measurement of rat LRG
- Sensitivity: Optimized for detecting low concentrations of LRG
- Format: Includes ready-to-use reagents and a detailed protocol
- Sample Types: Suitable for serum, CSF, and other relevant biological samples
Utility: The LRG ELISA Kit is ideal for:
- Measuring LRG levels in research on rheumatoid arthritis and idiopathic normal pressure hydrocephalus
- Monitoring treatment response and disease progression in RA patients
- Differentiating iNPH from other neurodegenerative diseases and evaluating shunt therapy effectiveness
Additional Information: A separate control set for the LRG ELISA Kit is available upon request. The kit is distributed by IBL International, ensuring high-quality and reliable measurement of LRG.
This ELISA Kit from Tecan IBL International is for research use only.
Tecan IBL International offers a comprehensive range of ELISAs, immunoassays, antibodies and recombinant proteins.
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