R10 is nanopore chemistry designed to deliver highest consensus accuracy. Paired with the Kit 14 chemistry, R10.4.1 generates data at a modal accuracy above 99%.
A Oxford Nanopore PromethION Flow Cell (R10.4.1) is a consumable used with PromethION devices. It contains the proprietary sensor array, Application-Specific Integrated Circuit (ASIC), and R10 nanopores. The R10 series of nanopores contains a double reader-head, and is suitable for experiments where high consensus accuracy is required. Paired with the Kit 14 chemistry, R10.4.1 generates data at a modal accuracy above 99%.
Note: All flow cells will be shipped with flow cell light shields.
How it works:
A user simply adds their prepared library to the flow cell, installs the light shield and starts their sequencing experiment.
Data is accumulated over time as DNA or RNA is sequenced by the nanopores. Individual read files are generated and are immediately available for analysis.
As data is streamed in real-time, a user can choose to stop a run as soon as sufficient data is gathered. A flow cell contains sufficient buffer to run for ~72 hours (under optimal conditions) and a user can choose to run continuously or run, stop, wash, and load a new sample until the buffer and nanopores are exhausted.