Bioprocessing Osmometer, OsmoTECH HT, Automated Micro-Osmometer, 0-2000 mOsm/kg H2O

Advanced Instruments OsmoTECH HT Automated Micro-Osmometer optimizes high-throughput osmolality testing with a 96-well plate format, small 40 µL sample volume, and seamless automation integration. Designed for bioprocessing workflows, it supports automation-friendly features, reliable performance, and compliance with 21 CFR Part 11 to streamline early process development, formulation screening, and drug formulation. Ideal for labs with high sample volumes and automation needs.

Optimize your high-throughput osmolality testing workflow

• Automation-friendly 96-well plate-based format for high-throughput testing
• Preserve sample with small testing volume
• Powerful data integrity and management features for easy data tracking and compliance

96 Well Plate-Based Osmometer for High-Throughput Labs

The OsmoTECH HT Automated Micro-Osmometer, is the only plate-based micro-osmometer currently available to support the growing automation and high throughput needs in bioprocessing. Designed in a 96-well format this automation-friendly instrument ensures efficiency and acceleration of osmolality testing in early process development, formulation screening, and formulation development workflows.

Highlighted features

• Automation-friendly 96-well plate-based format
• Small sample volume requirement
• Reliable and consistent performance
• Robust data integrity
• Flexible and secure data management
• Easy to use

Built for your process development and drug formulation needs

High-throughput bioprocess development involves many complex workflows. Between the need to perform osmolality testing on large numbers of samples and monitor multiple additional parameters, optimizing your lab’s workflows is critical. Automation-friendly features support your high-throughput environment, streamlining efficiency and reducing hands-on operator time.

Product Features

Effortlessly run multiple samples

• Plate-loading format allows samples to be robotically pipetted
• 96-well plate
• Load up to two plates for 192 tests

Automation-friendly workflows

• Streamline efficiency
• Reduce hands-on operator time
• Seamless integration with automation workflows (Ambr®, Cedex®, and liquid handling automation systems)

Minimize testing downtime

• Perform up to 1,000 tests before a consumables change is required
• Uninterrupted sample testing overnight and weekends

Conserve vital samples

• Only 40 µL sample volume needed for early process osmolality testing
• 20 µL for STAT testing

User-friendly interface

• Touchscreen interface
• Step-by-step guides for tests
• Easy access to test and consumable status

Assure accuracy

• Seal plate with custom cover to prevent evaporation and ensure repeatable and reliable results

Flexible and secure data management

• Save data to a network database, USB device or web server
• Automate the process with bi-directional communication to eliminate transcription errors and save time
• Easily integrate results into a data management system and batch records with OPC-UA

Automated self-cleaning

• Automated sampling and fluid cleaning
• Eliminate sample carryover and cross-contamination

Customizable templates

• Develop and store templates
• Reduce set-up time

Support compliance

• 21 CFR part 11 compliant
• Ease of implementation into a GMP environment

Backed by comprehensive support

• Purchase instruments with peace of mind
• Knowledgeable, experienced, and responsive support team

Upstream Manufacturing Applications

Clone Screening - Speed to market, boost cell longevity, increase yield and reduce production costs. Know more about your clones sooner and select the best clones earlier in the process.

Cell Line Development - Boost cell longevity and maximize cell productivity. Optimize osmolality when developing new feeds and additives in cell culture to increase cell longevity.

Formulation Development - Accelerate formulation development and stability testing. Integrate into automated workflows providing excipient concentrations and confirm the soluble content of formulations.