Push Boundaries with The New Breakthrough Technology for ASO, miRNA, and siRNA Detection
Detections of small non-coding RNAs such as microRNAs and short oligonucleotide therapeutics such as ASO and siRNA require a robust, highly specific and sensitive assay with minimal time and effort, delivering data for easy interpretation. While microarrays and PCR both provide useful molecular profiles of diseases, important clinically relevant cell and tissue context information is lost along with the spatial variation of gene expression patterns. The miRNAscope™ Assay is a highly sensitive and specific in situ hybridization assay that allows for the visualization of ASO, miRNA, siRNA and other nucleic acid targets between 17-50 nucleotides expression in intact tissues or cultured cells with single-cell resolution, preserving spatial and morphological context.
The miRNAscope™ Assay is available for both the manual and automated (Leica Systems, LS) platforms.